Key findings Data from the National Vital Statistics System, Mortality
â— In 2016, there were more than 63,600 drug overdose deaths in the United States.
â— The age-adjusted rate of drug overdose deaths in 2016 (19.8 per 100,000) was 21% higher than the rate in 2015 (16.3).
â— Among persons aged 15 and over, adults aged 25—34, 35—44, and 45—54 had the highest rates of drug overdose deaths in 2016 at around 35 per 100,000.
â— West Virginia (52.0 per 100,000), Ohio (39.1), New Hampshire (39.0), the District of Columbia (38.8), and Pennsylvania (37.9) had the highest observed age-adjusted drug overdose death rates in 2016.
â— The age-adjusted rate of drug overdose deaths involving synthetic opioids other than methadone (drugs such as fentanyl, fentanyl analogs, and tramadol) doubled between 2015 and 2016, from 3.1 to 6.2 per 100,000.
Complete Report Drug Overdose Deaths in the United States, 1999—2016